Article
Biological implications of SNPs in signal peptide domains of human proteins.
Proteins - 1 Feb 2008
Jarjanazi Hamdi, Savas Sevtap, Pabalan Noel, Dennis James W, Ozcelik Hilmi
Abstract excerpt
Proteins destined for secretion or membrane compartments possess signal peptides for insertion into the membrane. The signal peptide is therefore critical for localization and function of cell surface receptors and ligands that mediate cell-cell communication. About 4% of all human proteins liste...
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