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Article

Changes in predicted protein disorder tendency may contribute to disease risk.

BMC genomics - 23 Dec 2011

Hu Yang, Liu Yunlong, Jung Jeesun, Dunker A Keith, Wang Yadong

Abstract excerpt

BACKGROUND: Recent studies suggest that many proteins or regions of proteins lack 3D structure. Defined as intrinsically disordered proteins, these proteins/peptides are functionally important. Recent advances in next generation sequencing technologies enable genome-wide identification of novel nucleotide variations in a specific population or cohort. RESULTS: Using the exonic single nucleotide variations (SNVs)...

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Identifiers

PMID: 22369681
DOI: 10.1186/1471-2164-12-S5-S2
PMCID: PMC3287498

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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