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Article

Familial thoracic aortic dilation and bicommissural aortic valve: A prospective analysis of natural history and inheritance

3 Aug 2007

Abstract excerpt

The autosomal dominant inheritance of bicommissural aortic valve (BAV) (Online Mendelian Inheritance in Man #109730) in some families is well-documented; however, the inheritance of BAV with thoracic aortic aneurysm (TAA) is less clear. Whether the aneurysm is secondary to hemodynamic perturbation related to the valve abnormality or a primary manifestation of the disorder remains controversial. Guidelines are...

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PMID: 17676603
DOI: 10.1002/ajmg.a.31872

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