A roadmap to investigate the genetic basis of bicuspid aortic valve and its complications: insights from the International BAVCon (Bicuspid Aortic Valve Consortium).

doi:10.1016/j.jacc.2014.04.073

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A roadmap to investigate the genetic basis of bicuspid aortic valve and its complications: insights from the International BAVCon (Bicuspid Aortic Valve Consortium).

Journal of the American College of Cardiology - 26 Aug 2014

Prakash Siddharth K, Bossé Yohan, Muehlschlegel Jochen D, Michelena Hector I, Limongelli Giuseppe, Della Corte Alessandro, Pluchinotta Francesca R, Russo Maria Giovanna, Evangelista Artur, Benson D Woodrow, Body Simon C, Milewicz Dianna M

Abstract excerpt

Bicuspid aortic valve (BAV) is the most common adult congenital heart defect and is found in 0.5% to 2.0% of the general population. The term "BAV" refers to a heterogeneous group of disorders characterized by diverse aortic valve malformations with associated aortopathy, congenital heart defects, and genetic syndromes. Even after decades of investigation, the genetic determinants of BAV and its complications...

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A roadmap to investigate the genetic basis of bicuspid aortic valve and its complications: insights from the International BAVCon (Bicuspid Aortic Valve Consortium).

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