Article
Bicuspid aortic valve is heritable.
Journal of the American College of Cardiology - 7 Jul 2004
Cripe Linda, Andelfinger Gregor, Martin Lisa J, Shooner Kerry, Benson D Woodrow
Abstract excerpt
OBJECTIVES: Previous studies have established familial clustering of bicuspid aortic valve (BAV), presumably indicating genetic inheritance. Our objective was to statistically test whether the segregation pattern of BAV is consistent with genetic inheritance and to obtain an estimate of the size of the genetic effect (heritability). BACKGROUND: Bicuspid aortic valve occurs in 1% of the population, making it the...
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