Loss of expression of the uvomorulin gene in compaction-defective embryonal carcinoma cells.

doi:10.1007/BF01233627

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Article

Loss of expression of the uvomorulin gene in compaction-defective embryonal carcinoma cells.

Somatic cell and molecular genetics - 1 Nov 1991

Weng D E, Littlefield J W

Abstract excerpt

The lack of uvomorulin protein in the 6B(NG)C25 subline of H6 embryonal carcinoma cells is due to loss of expression of the uvomorulin gene, without evidence of gross alteration in the gene itself. This suggests that the dominant mutation in 6B(NG)C25 may involve a trans-acting factor involved in...

Topics

Animals
Blotting, Northern
Blotting, Southern
Cadherins
Mutation
Nucleic Acid Hybridization
Teratoma
Tumor Cells, Cultured

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