Article
Human papillomavirus genotyping after denaturation of specimens for Hybrid Capture 2 testing: feasibility study for the HPV persistence and progression cohort.
Journal of virological methods - 1 Dec 2007
LaMere Brandon J, Kornegay Janet, Fetterman Barbara, Sadorra Mark, Shieh Jen, Castle Philip E
Abstract excerpt
Human papillomavirus (HPV) genotyping could be clinically useful, depending on the results of large, prospective studies like the HPV persistence and progression (PaP) cohort. The cohort is based on genotyping and follow-up of Hybrid Capture-positive women at Kaiser Permanente, Northern California. HPV DNA testing by Hybrid Capture 2 requires denaturation with alkali, possibly damaging the DNA for optimal...
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