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Article

Human papillomavirus genotype specificity of hybrid capture 2.

Journal of clinical microbiology - 1 Aug 2008

Castle Philip E, Solomon Diane, Wheeler Cosette M, Gravitt Patti E, Wacholder Sholom, Schiffman Mark

Abstract excerpt

Hybrid Capture 2 (hc2), a clinical test for carcinogenic human papillomavirus (HPV) DNA, has proven to be a sensitive but only modestly specific predictor of cervical precancer and cancer risk. Some of its nonspecificity for clinical end points can be ascribed to cross-reactivity with noncarcinogenic HPV genotypes. However, the reference genotyping tests that have been used for these comparisons are also...

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Identifiers

PMID: 18579716
DOI: 10.1128/JCM.00824-08
PMCID: PMC2519476

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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