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Article

HPV genotype detection using hybrid capture sample preparation combined with whole genome amplification and multiplex detection with Luminex XMAP.

The Journal of molecular diagnostics : JMD - 1 Nov 2010

Lowe Brian, Kobayashi Lori, Lorincz Attila, Mallonee Rick, O'Neil Dominic, Thai Ha, Nazarenko Irina

Abstract excerpt

Infection with a high-risk carcinogenic type of human papillomavirus (HPV) is necessary for the development of cervical cancer. The digene HC2 HPV Test (HC2) is an important screening tool but lacks genotyping capability. To address this issue, we developed an assay for the rapid genotyping of HPV in cervical specimens. The three steps of this assay include Hybrid Capture target enrichment, whole-genome...

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Identifiers

PMID: 20847281
DOI: 10.2353/jmoldx.2010.100045
PMCID: PMC2963909

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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