Article
Grade-specific prostate cancer associations of IGF1 (CA)19 repeats and IGFBP3-202A/C in blacks and whites.
Journal of the National Medical Association - 1 Jul 2007
Hoyo Cathrine, Grubber Janet, Demark-Wahnefried Wendy, Marks Jeffrey R, Freedland Stephen J, Jeffreys Amy S, Grambow Steven C, Wenham Robert M, Walther Philip J, Schildkraut Joellen M
Abstract excerpt
Carrying the cytosine-adenosine (CA)19 repeat polymorphism in insulin-like growth factor-1 (IGF1) is associated with lower serum proteins and decreased prostate cancer risk. Carrying the -202A/C genotype in insulin-like growth factor binding protein-3 (IGFBP3) also has been associated with lower serum levels of the binding protein. However, the association between this variant and prostate cancer is inconsistent....
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