Article
A common genetic background for inflammatory bowel disease and ankylosing spondylitis: a genealogic study in Iceland.
Arthritis and rheumatism - 1 Aug 2007
Thjodleifsson Bjarni, Geirsson Arni J, Björnsson Sigurdur, Bjarnason Ingvar
Abstract excerpt
OBJECTIVE: Patients with ankylosing spondylitis (AS) and approximately 50% of their first-degree relatives may have a genetic abnormality that results in subclinical intestinal inflammation. This study was undertaken to examine the familial occurrence and cosegregation of AS and inflammatory bowel disease (IBD) in order to determine whether there is a shared genetic risk factor in families. METHODS: The Icelandic...
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