Article
Subclinical intestinal inflammation and sacroiliac changes in relatives of patients with ankylosing spondylitis.
Gastroenterology - 1 Dec 2003
Bjarnason Ingvar, Helgason Kristjan O, Geirsson Arni J, Sigthorsson Gudmundur, Reynisdottir Inga, Gudbjartsson Daniel, Einarsdottir Anna S, Sherwood Roy, Kristjansson Kristleifur, Kjartansson Olafur, Thjodleifsson Bjarni
Abstract excerpt
BACKGROUND & AIMS: It has been suggested that subclinical intestinal inflammation plays a pathogenic role in the spondylarthropathy of ankylosing spondylitis (AS). We assessed the possible presence and inheritance pattern of subclinical intestinal inflammation in first-degree relatives of patients with AS. The relationship between this inflammation and the subjects' HLA-B27 genotype as well as computerized...
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