Article
Rapid evolution, genetic variations, and functional association of the human spermatogenesis-related gene NYD-SP12.
Journal of molecular evolution - 1 Aug 2007
Zhang Qü, Zhang Feng, Chen Xiao-Hua, Wang Yin-Qiu, Wang Wei-Qi, Lin Alice A, Cavalli-Sforza Luca L, Jin Li, Huo Ran, Sha Jia-Hao, Li Zheng, Su Bing
Abstract excerpt
NYD-SP12 is a recently identified spermatogenesis-related gene with a pivotal role in human testis development. In this study, we analyzed between-species divergence and within-species variation of NYD-SP12 in seven representative primate species, four worldwide human populations, and 124 human clinical subjects. Our results indicate that NYD-SP12 evolves rapidly in both the human and the chimpanzee lineages,...
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