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A mutation modulating DDX3Y gene expression cosegregates with the major Y-chromosomal haplogroups and with testis size in Hu sheep.

Animal genetics - 1 Apr 2022

Zhang Xueying, Liao Zhi, Tang Shijie, Yuan Zehu, Li Fadi, Yue Xiangpeng

Abstract excerpt

Variations in the Y-chromosome are usually correlated with male-specific traits. However, this condition has been described only sporadically, even in human genetics. The present study was conducted to clone the full-length gene sequence of ovine DEAD-box helicase 3, Y-linked (DDX3Y), and investigate the effect of the expression and variation of DDX3Y on the reproductive traits of Hu sheep. Consequently, we...

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PMID: 34963194
DOI: 10.1111/age.13166

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