Article
Molecular cloning of the uaY regulatory gene of Aspergillus nidulans reveals a favoured region for DNA insertions.
Molecular & general genetics : MGG - 1 Dec 1991
Suárez T, Oestreicher N, Peñalva M A, Scazzocchio C
Abstract excerpt
The cloning of the positive regulatory gene, uaY, which mediates uric acid induction of enzymes and permeases of the purine degradation pathway in the fungus Aspergillus nidulans is described here. The 4 kb uaY transcript is constitutively synthesised, it is not repressed by ammonia and its transcription does not require the AreA wide-domain transcription factor. We have determined that four deletions, which have...
Topics
- Alleles
- Ammonia
- Aspergillus nidulans
- Chromosome Deletion
- Cloning, Molecular
- DNA, Fungal
- Gene Conversion
- Genes, Fungal
- Genes, Regulator
- Mutation
- Purines