Sequence, regulation, and mutational analysis of the gene encoding urate oxidase in Aspergillus nidulans.

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Article

Sequence, regulation, and mutational analysis of the gene encoding urate oxidase in Aspergillus nidulans.

The Journal of biological chemistry - 5 Nov 1993

Oestreicher N, Scazzocchio C

Abstract excerpt

The uaZ gene of Aspergillus nidulans codes for a protein of 301 amino acids. The open reading frame is interrupted by two introns. A comparison with the open reading frames of 10 other urate oxidases reveals a number of scattered universally conserved residues and four clusters of high similarity. Two of these are of unknown function, and the other two are the putative sites for copper binding and the signal...

Topics

Alleles
Amino Acid Sequence
Aspergillus nidulans
Base Sequence
DNA Primers
Gene Expression Regulation, Fungal
Genes, Fungal
Molecular Sequence Data
Mutagenesis, Site-Directed
Point Mutation
RNA, Messenger

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Recombinant Proteins

Regulatory Sequences, Nucleic Acid

Restriction Mapping

Sequence Alignment

Sequence Homology, Amino Acid

Structure-Activity Relationship

Transcription, Genetic

Source

Open in PubMed

Identifiers

PMID: 8226863

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-8226863-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Sequence, regulation, and mutational analysis of the gene encoding urate oxidase in Aspergillus nidulans.PMID 8226863Read ↗

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