Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Brain tau expression and correlation with the H1/H1 tau genotype in frontotemporal lobar degeneration patients.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Jan 2007

Lladó A, Ezquerra M, Gaig C, Sánchez-Valle R, Tolosa E, Molinuevo J L

Abstract excerpt

Alterations in tau mRNA splicing and association with H1/H1 tau genotype have been described in some sporadic tauopathies. We evaluated the 4R/3R tau mRNA ratio in 18 patients with frontotemporal lobar degeneration (FTLD), and the effect of the H1/H1 genotype on this ratio. The 4R/3R mRNA ratio in frontal cortex was similar in FTLD patients and controls. The H1/H1 genotype carriers showed a significant increase...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Brain

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Dementia

Share to Gene Expression

Share to Protein Isoforms

Share to Reverse Transcriptase Polymerase Chain Reaction

Share to RNA, Messenger

Share to tau Proteins

Source

Identifiers

PMID: 17661153
DOI: 10.1007/s00702-007-0786-5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Brain tau expression and correlation with the H1/H1 tau genotype in frontotemporal lobar degeneration patients.PMID 17661153Read ↗

Increase in the relative expression of tau with four microtubule binding repeat regions in frontotemporal lobar degeneration and progressive supranuclear palsy brains.Semantic proximity Read ↗

Association between the extended tau haplotype and frontotemporal dementia.Semantic proximity Read ↗

Tau alternative splicing and frontotemporal dementia.Semantic proximity Read ↗

H1 haplotype of the MAPT gene is associated with lower regional gray matter volume in healthy carriers.Semantic proximity Read ↗

Possible association of the tau H1/H1 genotype with primary progressive aphasia.Semantic proximity Read ↗

The effect of tau genotype on clinical features in FTDP-17.Semantic proximity Read ↗

The tau gene haplotype h1 confers a susceptibility to Parkinson's disease.Semantic proximity Read ↗

The tau H1 haplotype is associated with Parkinson's disease in the Norwegian population.Semantic proximity Read ↗

Haplotype-specific expression of exon 10 at the human MAPT locus.Semantic proximity Read ↗

Clinical and genetic features of families with frontotemporal dementia and parkinsonism linked to chromosome 17 with a P301S tau mutation.Semantic proximity Read ↗

Association of the Tau haplotype with Parkinson's disease in the Greek population.Semantic proximity Read ↗

Tau haplotype influences cerebral perfusion pattern in frontotemporal lobar degeneration and related disorders.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.