Article
Algorithms to distinguish the role of gene-conversion from single-crossover recombination in the derivation of SNP sequences in populations.
Journal of computational biology : a journal of computational molecular cell biology - 1 Dec 2007
Song Yun S, Ding Zhihong, Gusfield Dan, Langley Charles H, Wu Yufeng
Abstract excerpt
Meiotic recombination is a fundamental biological event and one of the principal evolutionary forces responsible for shaping genetic variation within species. In addition to its fundamental role, recombination is central to several critical applied problems. The most important example is "association mapping" in populations, which is widely hoped to help find genes that influence genetic diseases (Carlson et al.,...
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