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Article

Arabidopsis auxin-resistance gene AXR1 encodes a protein related to ubiquitin-activating enzyme E1.

Nature - 8 Jul 1993

Leyser H M, Lincoln C A, Timpte C, Lammer D, Turner J, Estelle M

Abstract excerpt

The plant hormone auxin has a central role in many aspects of plant growth and development. By screening for mutants of Arabidopsis that are resistant to exogenous auxin, we have identified several genes that are required for normal auxin response. One of these genes, AXR1, is defined by recessive mutations that confer auxin resistance to the roots, rosettes and inflorescences of mutant plants. In addition, axr1...

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PMID: 8321287
DOI: 10.1038/364161a0

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Arabidopsis auxin-resistance gene AXR1 encodes a protein related to ubiquitin-activating enzyme E1.PMID 8321287Read ↗

AXR1-ECR1 and AXL1-ECR1 heterodimeric RUB-activating enzymes diverge in function in Arabidopsis thaliana.Semantic proximity Read ↗

The ubiquitin-related protein RUB1 and auxin response in Arabidopsis.Semantic proximity Read ↗

Growth and development of the axr1 mutants of Arabidopsis.Semantic proximity Read ↗

AXR2 encodes a member of the Aux/IAA protein family.Semantic proximity Read ↗

The TIR1 protein of Arabidopsis functions in auxin response and is related to human SKP2 and yeast grr1p.Semantic proximity Read ↗

The IAA1 protein is encoded by AXR5 and is a substrate of SCF(TIR1).Semantic proximity Read ↗

Mutation of E1-CONJUGATING ENZYME-RELATED1 decreases RELATED TO UBIQUITIN conjugation and alters auxin response and development.Semantic proximity Read ↗

AXR1-ECR1-dependent conjugation of RUB1 to the Arabidopsis Cullin AtCUL1 is required for auxin response.Semantic proximity Read ↗

Cloning and characterization of IAR1, a gene required for auxin conjugate sensitivity in Arabidopsis.Semantic proximity Read ↗

A new temperature-insensitive allele of the Arabidopsis AXR6/CUL1 locus derived from a missense mutation in the C-terminal RBX1 binding region.Semantic proximity Read ↗

DENEDDYLASE1 Protein Counters Automodification of Neddylating Enzymes to Maintain NEDD8 Protein Homeostasis in Arabidopsis.Semantic proximity Read ↗

AXR4 is required for localization of the auxin influx facilitator AUX1.Semantic proximity Read ↗

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