Article
[Host's genetics in HIV disease].
Pathologie-biologie - 1 Jan 2013
Bouthemy C, Nel I, Oudot Mellakh T, Theodorou I
Abstract excerpt
In the 1990 s, the variability of responses to human immunodeficiency virus (HIV) could only be tracked by phenotypic criteria such as the number of CD4T lymphocytes, the occurrence of opportunistic infection, the disease free survival without treatment. In 1996, the viral load is the leading phenotype for genetic studies. Ever since, thanks to a better understanding of the HIV infection pathophysiology, numerous...
Topics
- Disease Progression
- Genes, MHC Class I
- Genetic Predisposition to Disease
- HIV Infections
- HIV-1
- Host-Pathogen Interactions
- Humans
- Receptors, CCR5