Article
[Host genetic polymorphisms in the pathogenesis of HIV-1 disease].
Nihon rinsho. Japanese journal of clinical medicine - 1 Apr 2002
Nakayama Emi E, Shioda Tatsuo
Abstract excerpt
HIV-1 infection is generally characterized by a long-term, chronic disease course gradually progressing to AIDS. However, there are a few but strikingly different scenarios. A small fraction of HIV-1 infections remains normal both clinically and immunologically over 10 years or more after seroconversion. Conversely, another marked fraction is featured by an extremely rapid disease progression taking place even...
Topics
- Acquired Immunodeficiency Syndrome
- Chemokines
- Disease Progression
- Genetic Predisposition to Disease
- HIV-1
- Humans
- Polymorphism, Genetic
- Receptors, Chemokine
