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Persistent Host Markers in Pandemic and H5N1 Influenza Viruses

26 Jul 2007

Abstract excerpt

Avian influenza viruses have adapted to human hosts, causing pandemics in humans. The key host-specific amino acid mutations required for an avian influenza virus to function in humans are unknown. Through multiple-sequence alignment and statistical testing of each aligned amino acid, we identified markers that discriminate human influenza viruses from avian influenza viruses. We applied strict thresholds to...

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Identifiers

PMID: 17652405
DOI: 10.1128/jvi.00921-07

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