Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Primary isolates of human immunodeficiency virus type 1 are usually dominated by the major variants found in blood.

Journal of virology - 1 Oct 2007

Voronin Yegor, Chohan Bhavna, Emerman Michael, Overbaugh Julie

Abstract excerpt

The isolation of primary strains of human immunodeficiency virus (HIV) is an invaluable tool for assessing properties of viruses replicating in HIV-infected subjects. A common method for obtaining a primary isolate is coculture of peripheral blood mononuclear cells (PBMCs) from HIV-infected subjects with PBMCs from uninfected donors. However, such in vitro expansion may disturb the composition (identities and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Blood
Share to Coculture Techniques
Share to HIV-1

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HIV Envelope Protein gp120

Share to Leukocytes, Mononuclear

Share to Phylogeny

Share to Polymerase Chain Reaction

Share to Sequence Analysis, DNA

Source

Open in PubMed Open full text

Identifiers

PMID: 17652386
DOI: 10.1128/JVI.01035-07
PMCID: PMC2045467

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Primary isolates of human immunodeficiency virus type 1 are usually dominated by the major variants found in blood.PMID 17652386Read ↗

In-depth characterization of viral isolates from plasma and cells compared with plasma circulating quasispecies in early HIV-1 infection.Semantic proximity Read ↗

The emerging genetic diversity of HIV. The importance of global surveillance for diagnostics, research, and prevention.Semantic proximity Read ↗

Selection of HIV-1 genotypes by cultivation in different primary cells.Semantic proximity Read ↗

Characterization of the viral population during primary HIV-1 infection.Semantic proximity Read ↗

Rapid generation of sequence variation during primary HIV-1 infection.Semantic proximity Read ↗

Extensive characterization of HIV-1 reservoirs reveals links to plasma viremia before and during analytical treatment interruptionSemantic proximity Read ↗

HIV evolution and diversity in ART-treated patients.Semantic proximity Read ↗

Effect of antiretroviral therapy on HIV-1 genetic evolution during acute infection.Semantic proximity Read ↗

Recovery of virtually full-length HIV-1 provirus of diverse subtypes from primary virus cultures using the polymerase chain reaction.Semantic proximity Read ↗

Clonal Sequences Recovered from Plasma from Patients with Residual HIV-1 Viremia and on Intensified Antiretroviral Therapy Are Identical to Replicating Viral RNAs Recovered from Circulating Resting CD4 <sup>+</sup> T CellsSemantic proximity Read ↗

Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID.Semantic proximity Read ↗

HIV-PULSE: a long-read sequencing assay for high-throughput near full-length HIV-1 proviral genome characterizationSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.