Article
Relationship of connexin43 expression to phenotypic modulation in cultured human aortic smooth muscle cells.
European journal of cell biology - 1 Oct 2007
Matsushita Tsutomu, Rama Aisha, Charolidi Nicoletta, Dupont Emmanuel, Severs Nicholas J
Abstract excerpt
Transition of arterial smooth muscle cells from the contractile to the synthetic phenotype in vivo is associated with up-regulation of the gap-junctional protein, connexin43 (Cx43). However, the role of increased Cx43 expression in relation to the characteristic features of the synthetic phenotype - altered growth, differentiation or synthetic activity - has not previously been defined. In the present study,...
Topics
- Angiogenesis Inducing Agents
- Aorta
- Becaplermin
- Blotting, Northern
- Blotting, Western
- Cell Communication
- Cell Differentiation
- Cell Proliferation
- Cells, Cultured
- Connexin 43
- Fluorescent Antibody Technique
- Gap Junctions
- Hemostatics
- Humans