Enhanced activity of strobilurin and fludioxonil by using berberine and phenolic compounds to target fungal antioxidative stress response.

doi:10.1111/j.1472-765X.2007.02159.x

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Enhanced activity of strobilurin and fludioxonil by using berberine and phenolic compounds to target fungal antioxidative stress response.

Letters in applied microbiology - 1 Aug 2007

Kim J H, Campbell B C, Mahoney N, Chan K L, Molyneux R J, May G S

Abstract excerpt

AIMS: Identify natural products that effectively target antioxidative signal transduction/stress response systems [i.e., mitogen-activated protein kinase (MAPK) pathway, mitochondrial superoxide dismutase (Mn-SOD)] of fungi. Enhance activity of strobilurin or fludioxonil with discovered compounds. METHODS AND RESULTS: Enhancement of antifungal activity of strobilurins, inhibitors of complex III of the...

Topics

Antifungal Agents
Aspergillus fumigatus
Berberine
Dioxanes
Dioxoles
Drug Synergism
Fungi
Heat-Shock Response
Methacrylates
Microbial Sensitivity Tests
Mutation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Oxidative Stress

Phenols

Pyrroles

Saccharomyces cerevisiae

Signal Transduction

Superoxide Dismutase

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Open in PubMed

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PMID: 17651208
DOI: 10.1111/j.1472-765X.2007.02159.x

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