Article
FcgammaRIIIA and FcgammaRIIA polymorphisms do not predict clinical outcome of follicular non-Hodgkin's lymphoma patients treated with sequential CHOP and rituximab.
Haematologica - 1 Aug 2007
Carlotti Emanuela, Palumbo Giuseppe A, Oldani Elena, Tibullo Daniele, Salmoiraghi Silvia, Rossi Andrea, Golay Josee, Pulsoni Alessandro, Foà Robin, Rambaldi Alessandro
Abstract excerpt
We analyzed FcgammaRIIIA-158V/F and FcgammaRIIA-131H/R polymorphisms in a cohort of 94 newly diagnosed follicular lymphoma (FL) patients sequentially treated with CHOP and Rituximab. With a median follow-up of 5.8 years, the overall survival at 8 years is 83%. Univariate and multivariate analysis showed no correlation between FcgammaRIIIA-158VV/VF and FcgammaRIIA-131HH/HR polymorphisms and the overall response...
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