Article
Semiparametric functional mapping of quantitative trait loci governing long-term HIV dynamics.
Bioinformatics (Oxford, England) - 1 Jul 2007
Wu Song, Yang Jie, Wu Rongling
Abstract excerpt
MOTIVATION: Functional mapping has proven to be powerful for characterizing quantitative trait loci (QTL) that control complex dynamic traits. More recently, functional mapping has been extended to identify the host QTL responsible for HIV dynamics by incorporating a parametric bi-exponential function for earlier stages of viral load trajectories. However, existing functional mapping cannot be used to map...
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