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Article

A maximum likelihood approach to functional mapping of longitudinal binary traits.

Statistical applications in genetics and molecular biology - 22 Nov 2012

Wang Chenguang, Li Hongying, Wang Zhong, Wang Yaqun, Wang Ningtao, Wang Zuoheng, Wu Rongling

Abstract excerpt

Despite their importance in biology and biomedicine, genetic mapping of binary traits that change over time has not been well explored. In this article, we develop a statistical model for mapping quantitative trait loci (QTLs) that govern longitudinal responses of binary traits. The model is constructed within the maximum likelihood framework by which the association between binary responses is modeled in terms...

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Identifiers

PMID: 23183762
DOI: 10.1515/1544-6115.1675
PMCID: PMC3856886

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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