Article
A nonlinear mixed-effect mixture model for functional mapping of dynamic traits.
Heredity - 1 Oct 2008
Hou W, Li H, Zhang B, Huang M, Wu R
Abstract excerpt
Functional mapping has emerged as a next-generation statistical tool for mapping quantitative trait loci (QTL) that affect complex dynamic traits. In this article, we incorporated the idea of nonlinear mixed-effect (NLME) models into the mixture-based framework of functional mapping, aimed to generalize the spectrum of applications for functional mapping. NLME-based functional mapping, implemented with the...
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