Article
[Biological diagnosis of Von Willebrand disease and its difficulties].
La Tunisie medicale - 1 Jun 2007
Znazen Raja, Guermazi Sami, Karoui Mongi
Abstract excerpt
Von Willebrand disease is the most common inherited bleeding disorder, with autosomal genetic transmission, dominant in most cases. It is due to quantitative and/or qualitative deficiency of Von Willebrand factor, a multimeric complex glycoprotein that plays 2 central roles in hemostasis, since it is implicated in adhesion and aggregation of platelets under conditions of high shear forces and acts as a carrier...
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