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Von willebrand disease: An overview

1 Jan 2011

Abstract excerpt

Most commonly inherited bleeding disorder, first described in Aland Islands by Erik von Willebrand. It occurs as a result of decrease in plasma levels or defect in von Willebrand factor which is a large multimeric glycoprotein. Monomers of this glycoprotein undergo N-glycosylation to form dimers which get arranged to give multimers. Binding with plasma proteins (especially factor VIII) is the main function of von...

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PMID: 22131616
DOI: 10.4103/0250-474x.89751

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