Congenital von Willebrand disease type I: definition, phenotypes, clinical and laboratory assessment.

Abstract excerpt

Von Willebrand disease, with a prevalence of about 1% in the general population, is the most frequent inherited bleeding disorder. Among the major subtypes, type I von Willebrand disease represents by far the more prevalent category (about 70%) and includes cases with a partial deficiency of plasma von Willebrand factor and no evidence of qualitative defects. The clinical expression as well as the laboratory...

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