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Article

Transcription factor E2F-1 is upregulated in human gastric cancer tissues and its overexpression suppresses gastric tumor cell proliferation.

Cellular oncology : the official journal of the International Society for Cellular Oncology - 1 Jan 2007

Xiao Qiang, Li Lei, Xie Yubo, Tan Ning, Wang Changqing, Xu Junyi, Xia Keyi, Gardner Kevin, Li Qingdi Q

Abstract excerpt

The E2F family members play a critical role in cell cycle regulation and other biological processes in the cell. To better understand the involvement of E2F-1 in the development and progression of gastric tumors, we investigated the mutation and expression of E2F-1 in human gastric cancer tissues and the effect of E2F-1 overexpression on the proliferation of gastric carcinoma cells. In this study, 80 pairs of...

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Identifiers

PMID: 17641417
DOI: 10.1155/2007/147615
PMCID: PMC4617805

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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