Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

E2F1 Maintains Gastric Cancer Stemness Properties by Regulating Stemness-Associated Genes

23 Apr 2021

Abstract excerpt

Purpose. To determine the regulatory role of E2F1 in maintaining gastric cancer stemness properties and the clinical significance of E2F1 in gastric cancer. Materials and Methods. We conducted a tumor spheroid formation assay to enrich gastric cancer stem-like cells. The protein and mRNA expression levels of genes were measured using Western Blot and qRT-PCR. Lentivirus-mediated overexpression and downregulation...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Autophagy in Disease and Therapy
Share to Cancer Cells and Metastasis
Share to Cancer-related Molecular Pathways

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 33986804
DOI: 10.1155/2021/6611327

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

E2F1 Maintains Gastric Cancer Stemness Properties by Regulating Stemness-Associated GenesPMID 33986804Read ↗

Requirement of transcription factor NME2 for the maintenance of the stemness of gastric cancer stem-like cellsSemantic proximity Read ↗

Identification of key genes controlling cancer stem cell characteristics in gastric cancerSemantic proximity Read ↗

Transcription Elongation Factor A-like 7 is a Stemness-Related Prognostic Factor in Gastric CancerSemantic proximity Read ↗

Emerging Role of E2F Family in Cancer Stem CellsSemantic proximity Read ↗

Identification of Key Genes for Controlling Cancer Stem Cell Characteristics in Gastric CancerSemantic proximity Read ↗

Targeting Gastric Cancer Stem Cells to Enhance Treatment ResponseSemantic proximity Read ↗

Comprehensive analysis of transcriptome data stemness indices identifies key genes for controlling cancer stem cell characteristics in gastric cancerSemantic proximity Read ↗

NANOGP8 is the key regulator of stemness, EMT, Wnt pathway, chemoresistance, and other malignant phenotypes in gastric cancer cellsSemantic proximity Read ↗

Prognostic values of E2F mRNA expression in human gastric cancerSemantic proximity Read ↗

PRDM1 promotes the stemness of gastric cancer cells by enhancing the transactivation of MycSemantic proximity Read ↗

Identification of Stemness Characteristics Associated With the Immune Microenvironment and Prognosis in Gastric CancerSemantic proximity Read ↗

Stemness Is Enhanced in Gastric Cancer by a SET/PP2A/E2F1 AxisSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.