Back to search

Article

The roles of E2Fs in gastric cancer: the transcription factors E2F1/2/3/4/5 as potential therapeutic targets and E2F6/7/8 as new prognostic biomarkers in gastric cancer

2020-05-28

Abstract excerpt

<title>Abstract</title> <p>Background E2F is a family of transcription factor proteins with multiple functions; E2F proteins are involved in cell cycle regulation, cell differentiation, the DNA damage response and cell death. Studies have shown that E2Fs have prognostic significance in many cancers, but the expression patterns and prognostic values of E2Fs in gastric cancer have not been systematically elucidated...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work
14b9f01c-4b91-5045-873c-6187f5b40fe7
DOI
10.21203/rs.3.rs-31173/v1
Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest
Interactive article relationship graphSelect a related publication card to move it into the centre and load its closest explainable connections. Solid lines are source-backed structured connections. Dashed lines are semantic discovery signals and are not scientific evidence.
The roles of E2Fs in gastric cancer: the transcription factors E2F1/2/3/4/5 as potential therapeutic targets and E2F6/7/8 as new prognostic biomarkers in gastric cancerDOI 10.21203/rs.3.rs-31173/v1
Expression and prognostic value of E2F family members in gastric cancerSemantic proximity
Novel Potential Therapeutic Target for E2F1 and Prognostic Factors of E2F1/2/3/5/7/8 in Human Gastric CancerSemantic proximity
Prognostic values of E2F mRNA expression in human gastric cancerSemantic proximity
E2F2 inhibition induces autophagy to impair metastasis via the PI3K/Akt/mTOR pathway in gastric cancerSemantic proximity
E2F1 and E2F7 regulate gastric cancer cell proliferation, respectively, through transcriptional activation and transcriptional repression of MYBL2Semantic proximity
Gastric Cancer Based on Transcription FactorsSemantic proximity
Promising diagnostic and prognostic value of E2Fs in human hepatocellular carcinomaSemantic proximity
Prognostic Biomarkers Based On GUF1, EFTUD2 and GSPT1 Targets Affecting Migration of Gastric Cancer Cells.Semantic proximity
Identification of 7 key genes as biomarkers for prognosis and metastasis of gastric cancerSemantic proximity
A Research of the Predictive Values of E2F Factors in Colorectal CancerSemantic proximity
Identification of Function Genes regulating Gastric Cancer progression using Integrated Bioinformatics AnalysisSemantic proximity
Transcription Factors E2F2/3/4 As Possible Colorectal Cancer Prognostic BiomarkersSemantic proximity
Select a neighboring publication to make it the new centre.