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E2F2 inhibition induces autophagy to impair metastasis via the PI3K/Akt/mTOR pathway in gastric cancer

2020-10-29

Abstract excerpt

<h4>Background: </h4> E2F2 is a member of the E2F family of transcription factors with important yet incompletely understood biological functions in cancer. In some cancer types, controversial tumor-promoting and tumor-suppressive roles of E2F2 have been reported. However, the biological role of E2F2 in gastric cancer (GC) remains to be determined. <h4>Methods: </h4>: We analyzed E2F2 expression via multiple gene...

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Literature Corpus work
5a5e0d12-361f-5a66-8dac-3bb5814b3878
DOI
10.21203/rs.3.rs-97865/v1
Open publication

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