Article
Effects of long-term, low-dose sex hormone replacement therapy on hippocampus and cognition of postmenopausal women of different apoE genotypes.
Acta pharmacologica Sinica - 1 Aug 2007
Yue Yun, Hu Ling, Tian Qin-jie, Jiang Jing-mei, Dong Yi-long, Jin Zheng-yu, Cheng Yu-hang, Hong Xia, Ge Qin-sheng, Zuo Ping-ping
Abstract excerpt
AIM: To study the effects of long-term, low-dose sex hormone replacement therapy (HRT) on the volume and biochemical changes of the hippocampus in postmenopausal women carrying apolipoprotein E (apoE) gene epsilon3 or epsilon4. METHODS: Eighty-three postmenopausal women who had used a low dose of HRT for over 4 years were selected as the HRT group, and 99 postmenopausal women with matched age and education were...
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