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Hormone Replacement Therapy is associated with improved cognition and larger brain volumes in at risk APOE4 women: results from the European Prevention of Alzheimer’s Disease (EPAD) cohort

2022-07-22

Abstract excerpt

<title>Abstract</title> <p>Background:The risk of dementia is higher in women than men. The metabolic consequences of estrogen decline during menopause accelerates neuropathology in women. The use of hormone replacement therapy (HRT) in the prevention of cognitive decline has shown conflicting results. Here we investigate the modulating role of <italic>APOE</italic> genotype and age at HRT initiation on the heter...

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Literature Corpus work: afc8ef1a-81d0-528c-a595-09c0495ce3b9
DOI: 10.21203/rs.3.rs-1853899/v1

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