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Article

p53 and its isoforms in cancer.

British journal of cancer - 6 Aug 2007

Bourdon J-C

Abstract excerpt

p53, p63 and p73 are members of the p53 gene family involved in development, differentiation and response to cellular stress. p53 gene is a transcription factor essential for the prevention of cancer formation. The p53 pathway is ubiquitously lost in human cancer either by p53 gene mutation (60% of cancers) or by lost of cell signalling upstream and downstream of p53 in the remaining cancers expressing WTp53...

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Identifiers

PMID: 17637683
DOI: 10.1038/sj.bjc.6603886
PMCID: PMC2360320

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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