Article
p53 and its isoforms in cancer.
British journal of cancer - 6 Aug 2007
Bourdon J-C
Abstract excerpt
p53, p63 and p73 are members of the p53 gene family involved in development, differentiation and response to cellular stress. p53 gene is a transcription factor essential for the prevention of cancer formation. The p53 pathway is ubiquitously lost in human cancer either by p53 gene mutation (60%...
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