Polymorphisms in the 5'- and 3'-untranslated region of the VEGF gene and sporadic breast cancer risk and clinicopathologic characteristics.

doi:10.1007/s13277-010-0121-x

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Article

Polymorphisms in the 5'- and 3'-untranslated region of the VEGF gene and sporadic breast cancer risk and clinicopathologic characteristics.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Apr 2011

Oliveira Cristiane, Lourenço Gustavo J, Silva Priscilla M R, Cardoso-Filho Cassio, Favarelli Maira H C, Gonçales Neiva S L, Gurgel Maria S C, Lima Carmen S P

Abstract excerpt

The wild and the variant alleles of the C936T and G634C vascular endothelial grow factor (VEGF) polymorphisms seem to be linked to higher angiogenic phenotype than the remaining alleles and may act on breast cancer (BC) origin. We investigated the influence of the VEGF C936T and G634C polymorphisms on the occurrence and clinicopathologic characteristics of sporadic breast cancer (SBC) in 235 patients and 235...

Topics

Adult
Aged
Aged, 80 and over
Brazil
Breast Neoplasms
Carcinoma, Ductal, Breast
Case-Control Studies
Female
Gene Frequency
Genotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Middle Aged

Polymorphism, Genetic

Receptors, Estrogen

Risk Factors

Untranslated Regions

Vascular Endothelial Growth Factor A

Source

Open in PubMed

Identifiers

PMID: 20981515
DOI: 10.1007/s13277-010-0121-x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-20981515-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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