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Article

Formation of different abzymes in autoimmune‐prone MRL‐lpr/lpr mice is associated with changes in colony formation of haematopoietic progenitors

1 May 2007

Abstract excerpt

It was shown that IgGs from the sera of 2-7-month-old control non-autoimmune (CBA x C57BL)F1 and BALB/c mice and 2-3-month-old autoimmune prone MRL-lpr/lpr mice (conditionally healthy mice) are catalytically inactive. During spontaneous development of deep systemic lupus erythematosus (SLE)-like pathology a specific reorganization of immune system of these mice leads to conditions associated with a production of...

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PMID: 17635644
DOI: 10.1111/j.1582-4934.2007.00048.x

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