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Article

Monocytosis and accelerated activation of lymphocytes in C1q-deficient autoimmune-prone mice.

Immunology - 1 Sept 2004

Trendelenburg Marten, Manderson Anthony P, Fossati-Jimack Liliane, Walport Mark J, Botto Marina

Abstract excerpt

C1q deficiency has been shown to accelerate spontaneous autoimmunity in mice. We studied the time course of activation of monocytes and lymphocytes in autoimmune and non-autoimmune mice in the presence or absence of C1q as a disease accelerator. Autoimmune MRL\Mp.C1qa-\- and non-autoimmune C57BL\6.C1qa-\- mice were analysed at various time points between 6 and 33 weeks of age and compared to strain- and...

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Identifiers

PMID: 15312138
DOI: 10.1111/j.1365-2567.2004.01940.x
PMCID: PMC1782548

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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