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Article

Alternative splicing controls nuclear translocation of the cell cycle-regulated Nek2 kinase.

The Journal of biological chemistry - 7 Sept 2007

Wu Wenjuan, Baxter Joanne E, Wattam Samantha L, Hayward Daniel G, Fardilha Margarida, Knebel Axel, Ford Eleanor M, da Cruz e Silva Edgar F, Fry Andrew M

Abstract excerpt

Nek2 is a cell cycle-regulated serine/threonine protein kinase that is up-regulated in human cancers. Functionally, it is implicated in control of centrosome separation and bipolar spindle formation in mitotic cells and chromatin condensation in meiotic cells. Two major splice variants have been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 17626005
DOI: 10.1074/jbc.M704969200

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-17626005-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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