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Article

Novel variants in the SOHLH2 gene are implicated in human premature ovarian failure.

Fertility and sterility - 1 Apr 2014

Qin Yingying, Jiao Xue, Dalgleish Raymond, Vujovic Svetlana, Li Jin, Simpson Joe Leigh, Al-Azzawi Farook, Chen Zi-Jiang

Abstract excerpt

OBJECTIVE: To determine whether variants in the SOHLH2 gene contribute to human premature ovarian failure (POF) in different ethnicities. DESIGN: Case-control genetic study. SETTING: University hospitals. PATIENT(S): Chinese (364 cases) and Serbian (197 cases) women with nonsyndromic POF and ethnically matched controls. INTERVENTION(S): None. MAIN OUTCOME MEASURE(S): Variation analysis of the SOHLH2 gene....

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Identifiers

PMID: 24524832
DOI: 10.1016/j.fertnstert.2014.01.001

Genes

SOHLH2

Variants

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