Article
The pea mitochondrial nucleoside diphosphate kinase cleaves DNA and RNA.
FEBS letters - 24 Jul 2007
Hammargren Jenni, Salinas Thalia, Maréchal-Drouard Laurence, Knorpp Carina
Abstract excerpt
Here, we present the characterization of a plant NDPK exhibiting nuclease activity. This is the first identification of a nuclease localised in the intermembrane space of plant mitochondria. The recombinant pea NDPK3 protein cleaves not only supercoiled plasmid DNA, but also highly structured RNA molecules such as tRNAs or the 3'UTR of the atp9 mRNA suggesting that the NDPK3 nuclease activity has a structural...
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