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Article

Mitochondrial complex I gene variant associated with early age at onset in spinocerebellar ataxia type 2.

Archives of neurology - 1 Jul 2007

Simon David K, Zheng Kangni, Velázquez Luis, Santos Nieves, Almaguer Luis, Figueroa K Pattie, Pulst Stefan-M

Abstract excerpt

BACKGROUND: A common mitochondrial complex I gene polymorphism (10398G) is reported to be inversely associated with the risk of Parkinson disease. We hypothesized that this variant might have a protective effect on the central nervous system and therefore might delay the onset of symptoms in spin...

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Identifiers

PMID: 17620498
DOI: 10.1001/archneur.64.7.1042

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-17620498-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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