Article
Association of FLT3 polymorphisms with low BMD and risk of osteoporotic fracture in postmenopausal women.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research - 1 Nov 2007
Koh Jung-Min, Oh Bermseok, Lee Jong-Young, Lee Jong-Keuk, Kimm Kuchan, Park Byung Lae, Shin Hyoung Doo, Lee Il-Kwon, Kim Hyeoung-Joon, Hong Jung-Min, Kim Tae-Ho, Kim Ghi Su, Kim Shin-Yoon, Park Eui Kyun
Abstract excerpt
UNLABELLED: The genetic effects of FLT3 polymorphisms on BMD and fracture risk in postmenopausal women were studied. We found that FLT3+13348C>T polymorphism and haplotype 2 were significantly associated with low BMD and high risk of fracture. INTRODUCTION: FMS-related tyrosine kinase 3 (FLT3) has been shown to play a critical role in the development of myelolymphoid progenitors and in the development of...
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