Article
Association between platelet glycoprotein Ib-alpha and myocardial infarction: results of a pilot study performed in male and female patients from Sicily.
Annals of the New York Academy of Sciences - 1 Nov 2006
Candore Giuseppina, Piazza Giuseppina, Crivello Antonino, Grimaldi Maria Paola, Orlando Valentina, Caruso Marco, Caimi Gregorio, Hoffmann Enrico, Incalcaterra Egle, Lio Domenico, Caruso Calogero
Abstract excerpt
Myocardial infarction (AMI) is a complex multifactorial disorder. Platelet adhesion and thrombosis are pivotal events in the development of atherosclerotic lesions. Occlusive thrombus is almost exclusively initiated by plaque rupture and adhesion of platelets to subendothelial von Willebrand factor (vWf) by its specific platelet receptor, the alpha-chain of glycoprotein (GP) Ib-IX-V complex of the human...
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