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Article

Immunohistochemistry for PrPSc in natural scrapie reveals patterns which are associated with the PrP genotype.

Neuropathology and applied neurobiology - 1 Aug 2007

Spiropoulos J, Casalone C, Caramelli M, Simmons M M

Abstract excerpt

Immunohistochemistry for PrPSc is used widely in scrapie diagnosis. In natural scrapie cases the use of immunohistochemistry (IHC) has revealed the existence of up to 12 different morphological types of immunostained deposits. The significance of this pattern variability in relation to genotype has not been studied extensively in natural disease. In this study we recorded in detail PrPSc patterns at the obex...

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Source

Identifiers

PMID: 17617872
DOI: 10.1111/j.1365-2990.2007.00800.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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