Article
Frequencies of prion protein (PrP) genotypes and distribution of ages in 15 scrapie-affected flocks in Great Britain.
The Veterinary record - 3 Jan 2004
Tongue S C, Wilesmith J W, Cook C J
Abstract excerpt
The frequencies of prion protein (PrP) genotypes were investigated in 15 scrapie-affected flocks in Great Britain. The flocks were heterogeneous in the frequencies of different genotypes and alleles, and in their age distributions. The median flock frequency of animals with VRQ-containing genotypes was 21 per cent (range 2 to 82 per cent, mean 25 per cent). The VRQ-containing and other non-ARR genotypes made up...
Topics
- Alleles
- Animals
- Disease Outbreaks
- Gene Frequency
- Genotype
- PrPSc Proteins
- Scrapie
- Sheep
- United Kingdom